Welcome Guest [Log In] [Register]
Welcome to Wild Cats. We hope you enjoy your visit.

Wild Cats is a new forum which aims to build itself into a board with comprehensive information and informed discussion of both living and extinct members of the Felidae family. Hope you join us in achieving this aim. You're currently viewing our forum as a guest. This means you are limited to certain areas of the board and there are some features you can't use. If you join our community, you'll be able to access member-only sections, and use many member-only features such as customizing your profile, sending personal messages, and voting in polls. Registration is simple, fast, and completely free.


Join our community!


If you're already a member please log in to your account to access all of our features:

Username:   Password:
Add Reply
Feline Find: How the Tabby Cat Got Its Stripes
Topic Started: Sep 21 2012, 03:27 PM (2,360 Views)
Taipan
Member Avatar
Administrator
Feline Find: How the Tabby Cat Got Its Stripes

Stephanie Pappas, LiveScience Senior Writer
Date: 20 September 2012 Time: 02:00 PM ET

Posted Image
A tabby cat with a "blotched" color pattern.

From where does a tabby cat get its stripes? The same place cheetahs get their spots.

A new study finds the same gene that is responsible for the cheetah's color patterns causes a tabby's stripes. Mutations in this newly identified gene transform a tabby's typical striped pattern into a less familiar "blotched" look. In cheetahs, similar mutations smear spots into thick stripes.

"What this is, is the first connection of a gene involved in pattern formation in cats to their molecular status," said study researcher Stephen O'Brien of the National Laboratory for Cancer Research.


Now "we know where the mutation is in this particular gene" to cause the pattern changes, O'Brien told LiveScience.

Posted Image
A tabby cat with a typical mackerel striped pattern.

Stripes or spots?

O'Brien and his colleagues contributed to the original sequencing of the domestic cat genome, which was completed in 2007. Besides being interesting from a basic science standpoint, O'Brien said, cat genetics may help researchers understand human disease and genetic development. [The 10 Coolest Genomes Ever Sequenced]

One mystery of cat development is how cats have come to have such varied coats, from solid colors to "mackerel" tabby patterns of thin vertical stripes. The researchers were particularly interested in what turns the mackerel pattern into a "blotched" tabby pattern, seen more often in European cats than American ones.

A map of kitty pedigrees allowed the researchers to narrow down the genetic culprit to one region of the chromosome containing three large genes. They then sequenced the genomes of two batches of tabbies, one with blotched coats and the other striped ones, and narrowed the culprit further to a gene called Taqpep.

Three separate mutations of the Taqpep gene in the domestic cat and another mutation in the same gene in the king cheetah can cause the tabby pattern to go from striped to splotchy, and, in the cheetah, from spotty to striped, the researchers found. This means the gene has mutated multiple times across kitties' evolutionary history.

Posted Image
A regular cheetah (standing) and a king cheetah, showing off its broad back stripes.

Cat color blueprint

The Taqpep gene holds the blueprint for a molecule usually found on cell membranes and used for passing messages from outside the cell to the inside. A mutation of the gene causes color pattern changes by interfering with the deposition of pigment during development, O'Brien said.

O'Brien suspects the gene also has other functions. Membrane-communication molecules are often associated with the immune system, he said. The fact that this coat-color mutation occurred many times suggests that it may be doing something more useful for the cats than simply changing their spots and stripes. One possibility is that the genetic change influences immune function, he said, and that the coat color variations seen in cats are a side effect of that change.

"I think that probably there are other things to be discovered about this gene," O'Brien said.

http://www.livescience.com/23348-how-the-tabby-cat-got-its-stripes.html
Offline Profile Quote Post Goto Top
 
1 user reading this topic (1 Guest and 0 Anonymous)
« Previous Topic · Latest Felidae related news and info · Next Topic »
Add Reply